Browsing by Author "Schürch, Anita C."

Now showing items 1-2 of 2

    • A high-throughput multiplexing and selection strategy to complete bacterial genomes 

      Alonso, Sergio Arredondo; Pöntinen, Anna K.; Cleon, Francois Pierre Alexandre; Gladstone, Rebecca Ashley; Schürch, Anita C.; Johnsen, Pål Jarle; Samuelsen, Ørjan; Corander, Jukka (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-09)
      Background: Bacterial whole-genome sequencing based on short-read technologies often results in a draft assembly formed by contiguous sequences. The introduction of long-read sequencing technologies permits those contiguous sequences to be unambiguously bridged into complete genomes. However, the elevated costs associated with long-read sequencing frequently limit the number of bacterial isolates ...

    • Mge-cluster: a reference-free approach for typing bacterial plasmids 

      Alonso, Sergio Arredondo; Gladstone, Rebecca Ashley; Pöntinen, Anna Kaarina; Gama, João Alves; Schürch, Anita C.; Lanza, Val F.; Johnsen, Pål Jarle; Samuelsen, Ørjan; Tonkin-Hill, Gerry; Corander, Jukka (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-10)
      Extrachromosomal elements of bacterial cells such as plasmids are notorious for their importance in evolution and adaptation to changing ecology. However, high-resolution population-wide analysis of plasmids has only become accessible recently with the advent of scalable long-read sequencing technology. Current typing methods for the classification of plasmids remain limited in their scope which ...